The ab[x] toolkit is a comprehensive suite of software tools for processing, annotating and analyzing antibody repertoire data. At the core of the ab[x] toolkit is abstar, a robust tool for performing large-scale sequence pre-processing, germline gene assignment and primary annotation. Similar in function to IMGT’s High/V-QUEST, abstar is not throughput limited, capable of readily processing billions of antibody sequences. If you’d like to cite the ab[x] tookit, please reference the following manuscript: