baseline repertoire

the great repertoire project

exceptionally deep sequencing of circulating B cells from 10 healthy adult subjects

responses to immunization

elicitation of VRC01-class bnAb intermediates

prime/boost immunization of transgenic mice expressing germline VRC01 heavy chains

HIV bnAb development

PC63

longitudinal development of a VRC01-class bnAb lineage in Protocol C donor PC63

PC64

longitudinal development of a V2 apex bnAb lineage in Protocol C donor PC64

PC76

longitudinal development of a V3 glycan bnAb lineage in Protocol C donor PC76